McCaffrey didn’t have much trouble against a Vegas run defense that has been one of the league’s worst over the past month. His rushing score was his ninth of the season, while his receiving score was his first of 2026. CMC logged 28 routes on the day while Kaelon Black had just five routes and did not see a target from Brock Purdy. McCaffrey, with at least 15 carries in five games this year, has a spectacular Week 10 matchup against a miserable Dallas defense.

The statuesque Cousins was under duress from start to finish, often falling back as he threw the ball into tight windows. That led to three picks, which should have been four or five picks if 49ers defenders had been a little more sure handed. As usual, Cousins targeted Brock Bowers relentlessly, once again connecting with the superstar tight end for a touchdown. He nearly threw a second touchdown to Bowers in the second half. Cousins also had a touchdown to Michael Mayer called back on an offensive pass interference penalty. This was only Cousins’ second game of the year with less than two TD passes. Cousins will be a superflex option in Week 10 against the Seahawks.

Watkins’ big day was capped off by a second half 37-yard touchdown grab on a perfectly placed ball from Brock Purdy. Watkins, who had 56 yards on three receptions in Week 7, functioned as the Niners’ top wideout with Mike Evans (Achilles) out. Watkins led the Niners in pass routes against a lousy Raiders secondary. He’ll be in play as a WR3 option in Week 10 against the Cowboys if Evans remains sidelined.

Rapoport adds that Mahomes’ “elbow strain/sprain will be monitored over the next few days for pain and swelling.” Without getting too deep into the weeds, there are a few things to note. First off, Rapoport sometimes reports injury news optimistically. It would have been nice to see him actually report a “minor” injury, rather than not “major.” Secondly, “strain” typically refers to muscles and tendons, while “sprain” is often used for ligaments. Using both is a tad confusing. That said, Rapoport’s follow-up statement suggests Mahomes may have a chance to play in Week 10 against the Falcons. Updates will be provided as soon as news breaks. Stay tuned.

A week after getting 25 rushes, Washington was relegated to six carries in this one, as the Niners raced out to a big lead and never relented. Washington tied Ashton Jeanty for the team lead in rushing attempts. Neither back got it going against a tough 49ers front seven. Washington, who ran five routes against San Francisco, will continue to be a prototypical early-down bruiser who is sensitive to weekly game script. He should be benched in almost every format next week against the brutal Seahawks defense.

Jacobs exited early in the first quarter after his finger got caught in a defender’s facemask while he attempted a stiff arm. While he was never officially ruled out, Jacobs never returned to the field and was instead on the sideline in full uniform. According to Schneidman, the Packers plan to find a way for Jacobs to play through the injury, but he was unable to return in this one. Although, to be fair, he also wasn’t needed, as the Packers’ offense was in control throughout the evening. We assume Jacobs would see close to a normal workload if he is active for Week 10 against the Vikings, meaning fantasy manager can treat him as a strong RB2.

The fact that 54 yards is something to talk about says enough about the year Smith-Njigba is having, still handily leading the league in receiving despite the down performance. He remained the clear top dog through the air, receiving 10 targets on only 28 Lock pass attempts, largely confined to short area work as the Seahawks struggled to decipher the zone-heavy and two-high-heavy Arizona defense. Lock suffered an oblique injury in the third quarter that could place his Week 10 status in doubt, despite not missing an offensive snap, meaning fantasy managers of Smith-Njigba will want to monitor the situation ahead of a Week 10 meeting with the Raiders considering Sam Darnold remains unlikely to play with a multi-week injury.

Last year, when Herbert injured his left, non-throwing hand, his trainers stabilized the hand, with extra padding and tape applied to his middle finger. The exact same thing happened today. Herbert fended off a pass rusher with his left hand before bracing himself with the same hand as he fell. Fortunately, he remained in the game long enough to complete a 58-yard touchdown pass to Quentin Johnston. After a trip to the blue medical tent, Herbert was on the sideline, helmet on, with his left hand and middle finger heavily taped and padded. However, he did not return. The Chargers’ pass protection remains a huge problem, allowing eight sacks on the day. Before exiting, Herbert completed 13-of-23 passes for 193 yards, one touchdown and one interception, rushing once for seven yards. Herbert told reporters post-game that he does not expect his left middle finger to be an issue going forward. We will know more once he undergoes imaging. Stay tuned.

The lone incompletion directed toward McBride came on the team’s final play of the game when the veteran tight end was unable to corral an end zone target that was thrown slightly behind him on fourth and goal. McBride combined with alpha wide receiver Michael Wilson to account for 15 targets on 30 Minshew pass attempts, something we’d expect to continue forward give the current state of the team. The Cardinals get another difficult matchup against the Rams in Week 10, where McBride will remain a surefire TE1 in fantasy circles.

The lone Gardner Minshew incompletion directed toward Wilson was an end zone target late in the fourth quarter, a miss that would have salvaged a usable fantasy outing for the veteran receiver. Wilson was responsible for nearly one third of the total offensive output from a Cardinals offense that was held to under 200 yards by the stingy Seattle defense, finishing second on the team in targets behind the eight of tight end Trey McBride. He remains an upside WR2 ahead of another difficult test against the Rams in Week 10.